What is Ledderhose's disease?

Ledderhose disease, also called plantar fibromatosis, is a rare condition in which benign but often painful lumps form in the fascia (connective tissue) of the arch of the foot. These lumps can make walking and standing difficult and are similar to Dupuytren's disease, which affects the hands.

The most noticeable feature is hard lumps or bumps that form on the sole of the foot, usually near the heel or midfoot. The lumps can be painful, especially when pressure is applied while walking or standing. In some cases, the skin over the lumps can tighten.

The exact cause of Ledderhose disease is unknown, but it is considered a type of connective tissue disorder. Possible contributing factors include genetics, trauma to the foot, and certain systemic diseases.

A doctor can usually make a diagnosis based on physical examination and the characteristic symptoms. Treatment may include physical therapy, orthopedic insoles, and pain relievers and anti-inflammatory drugs. If these are not sufficient, corticosteroid injections or surgical treatments may be necessary.

Ledderhose disease is a chronic condition that can sometimes be progressive, but in many cases the symptoms can be well controlled with treatment. However, the lumps can return after treatment, especially after surgery. Regular follow-up and tailored treatment strategies are often necessary to manage the condition.

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605618/

Author: Prof. Dr. Dirk Devroey - Latest update: 2024-08-05 - Copyright: Clinifacts 2024