Is COVID-19 mortality higher in men?

COVID-19 mortality is higher in men than in women. This pattern has been observed worldwide and is supported by several studies and data analysis.

Globally, data shows that men have a higher mortality rate from COVID-19 compared to women. For example, data from the Centers for Disease Control and Prevention (CDC) and other international health organizations have consistently reported higher mortality rates in men.

Women generally have stronger and more effective immune systems than men, which may contribute to better defenses against infections like COVID-19. Estrogen, a hormone found in higher levels in women, may have a protective effect against serious infections. Testosterone, found in higher levels in men, may negatively impact the immune system.

Men have higher rates of smoking and alcohol use, which can increase the risk of serious lung disease and other complications. Men are less likely to seek medical care and often have less access to health care, which can lead to later diagnoses and poorer outcomes. Men have higher rates of certain comorbidities such as heart disease, hypertension, and diabetes, all of which are risk factors for more severe disease progression and higher mortality from COVID-19.

While the pattern of higher male mortality is seen globally, exact figures can vary by region, health care systems and population composition.

Source: https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm

Author: Prof. Dr. Dirk Devroey - Latest update: 2022-12-09 - Copyright: Clinifacts 2025