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Do Selenium and Coenzyme Q10 Help Against Aging?

Selenium and coenzyme Q10 are often mentioned in the context of aging and health, but it is important to look at their effects critically.

Selenium is a so-called antioxidant. It is an essential trace element that is part of antioxidant enzymes such as glutathione peroxidase. It supports the immune system and is important for the metabolism of thyroid hormones.

Coenzyme Q10 (also known as ubiquinone) plays a role in mitochondria in the production of energy (ATP). As an antioxidant, it helps neutralize free radicals.

The Kisel-10 Study (Sweden, 2013–2023) is a long-term study in which older adults (average age 78) received selenium and Q10 daily. This study was conducted among older adults with a lower than average selenium intake. The benefits, such as improved heart function, lower mortality from cardiovascular disease, and better quality of life, do not apply to everyone.

There is no evidence that these supplements actually slow, stop, or reverse the aging process. Excessive selenium intake can be harmful.

Selenium and coenzyme Q10 may slow functional decline, but only in older adults with deficiencies or increased oxidative stress, but they are not miracle cures or anti-aging pills.

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193120

Author: Prof. Dr. Dirk Devroey - Latest update: 2025-08-07 - Copyright: Clinifacts 2026

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