Is ciprofloxacin a dangerous antibiotic?

Ciprofloxacin is a commonly used antibiotic, but it can indeed have risks, especially if used incorrectly or for long periods of time.

Ciprofloxacin is effective against a broad spectrum of bacteria. It is often prescribed for urinary tract infections, lung infections (such as pneumonia), skin, bone, or intestinal infections, and for some forms of traveler's diarrhea. It is therefore a powerful and useful antibiotic when used correctly.

Most people tolerate ciprofloxacin well, but some side effects can be serious, and therefore it is now prescribed more cautiously than in the past.

Significant risks include tendon problems (tendinitis or tendon rupture). This occurs mainly in the elderly, people with kidney problems, or when using corticosteroids. Nerve damage can sometimes occur, sometimes causing persistent tingling or burning pain.

In some people, it causes psychological side effects such as anxiety, insomnia, confusion, or depression. Rarely, heart problems such as heart rhythm disturbances can occur. Diaphragm or aortic tears are very rare but serious. This is especially common in people with vascular problems or high blood pressure.

Ciprofloxacin is therefore not necessarily dangerous for everyone, but it is potentially dangerous if used unnecessarily or for long periods of time. Doctors currently only prescribe it if there is no safer alternative. Contact your doctor immediately if you have tendon or nerve problems.

Source: https://www.ema.europa.eu/en/news/fluoroquinolone-antibiotics-reminder-measures-reduce-risk-long-lasting-disabling-potentially-irreversible-side-effects

Author: Prof. Dr. Dirk Devroey - Latest update: 2025-10-24 - Copyright: Clinifacts 2026