Did the mRNA vaccine against COVID cause excess mortality?

There is no reliable evidence that mRNA vaccines against COVID-19 have led to excess mortality. Large, recent studies and international bodies have found no increase in all-cause mortality among vaccinated individuals.

Large-scale cohort analyses of millions of people found no increased 4-year all-cause mortality among mRNA vaccine recipients. Analysis studies estimate that COVID-19 vaccination prevented hundreds of thousands to millions of deaths worldwide in the period 2020–2024. This contradicts the idea that vaccines cause massive excess mortality.

WHO and national authorities are monitoring safety and have found no evidence that vaccines are responsible for excess mortality? Fact-checkers have refuted claims of vaccine-related excess mortality.

mRNA vaccines can (sometimes) be associated with myocarditis, especially in younger men, usually mild and rarely fatal. The risk of myocarditis and serious heart problems is greater after a SARS-CoV-2 infection than after vaccination.

Observations of increased excess mortality in some countries in 2022–2023 have been investigated. The causes are complex and include COVID waves, healthcare backlogs, other infections, and societal factors. One-sided conclusions about vaccine blame often lack proper causal analysis.

Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2842305

Author: Prof. Dr. Dirk Devroey - Latest update: 2025-12-06 - Copyright: Clinifacts 2026