What is endobiogeny?

Endobiogeny (or endobiogenic medicine) is an alternative medical approach that attempts to explain health and disease through the body's internal regulation, particularly through the hormonal and neuroendocrine systems.

It was developed in France in the second half of the 20th century by Christian Duraffourd and later further developed with Dr. Max Tétau, among others.

Endobiogeny is based on the idea that the body is a single dynamic regulatory system, primarily controlled by hormones and the autonomic nervous system, and that disease arises from imbalances in this regulation, not from a single defect.

Instead of a diagnosis based on a disease entity (e.g., high blood pressure), the patient's functional profile is considered (e.g., excessive cortisol dominance).

Endobiogeny involves performing a blood analysis with endobiogenic characteristics. Common blood values ​​(hemoglobin, white blood cells, salts, etc.) are used and combined into complex ratios that are said to indicate hormonal balance, stress response, inflammatory tendency, and metabolic activity. These indices have not been validated in conventional medicine.

Treatment often involves phytotherapy (plant extracts) and sometimes homeopathic or mixed preparations, with the aim of adjusting internal regulation, not suppressing the symptom.

There are no large, well-designed randomized studies demonstrating that endobiogeny is effectively beneficial.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC3833585/

Author: Prof. Dr. Dirk Devroey - Latest update: 2025-12-28 - Copyright: Clinifacts 2026